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Choosing an antibiotic

Consider patient factors:

  1. Allergy

  2. Renal and hepatic function

  3. Immune status

  4. Ability to tolerate oral medication

  5. Severity of the illness

  6. Pregnancy, breastfeeding, taking oral contraceptive?

Consider the organism :

  1. What is the likely organism?

  2. What is its likely or proven sensitivity?

Before starting therapy

  • Always take samples for C+S, do not prescribe blindly before samples taken

  • Dose will vary according to age, weight, renal function and severity of infection

  • Route of administration depends on the severity of the infection,

  • Duration of therapy, for most conditions 5 days is enough but for TB or osteomyelitis relatively long courses required

  • Remember the risk of superinfection (eg pseudomembranous colitis, candida) more likely with broad spectrum antibiotics


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Orthopaedic infections in children
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