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Bone Tumours

These are either:

  • primary or secondary
  • benign or malignant

Secondary bone tumours are much more common than primary bone tumours


Secondary bone tumours

The tumours which most commonly metastasise to bone (i.e. the primary tumours) are:

  1. BREAST
  2. BRONCHUS
  3. THYROID
  4. RENAL
  5. PROSTATE
  6. BOWEL

Location:
Metastases are found in the axial skeleton – spine, pelvis, ribs, long bones

Presentation:
in all cases the primary tumour may or may not be known

  • Bone pain – night pain common +/- constitutional symptoms (weight loss, fatigue)
  • Pathological fracture – tumour cells weaken bone by activating osteoclasts
  • Spinal cord compression – pressure of tumour on nerve roots causing leg weakness
  • Incidental – raised alkaline phosphatase on routine blood tests or osteolytic lesion on x-ray taken for another reason 

Investigations:



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