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Fibrogenic tumours

Benign

Fibrous Cortical defect (Non-ossifying fibroma)     [Back To Top] 

Incidence

  • A developmental defect in which a nest of fibrous tissue appears in the bone and persists for several years
  • 20% of benign bone lesions
  • Male more than Female

Clinically

  • Usually an incidental finding in children
  • Most heal spontaneously
  • Larger ones may -> pathological fracture (common presentation)

X-Rays

  • Lucent 
  • in the cortex of a long bone 
  • metaphyseal
  • eccentric
  • Margin well defined, sometimes scalloped and often sclerosed

Histology:  

  • whorled fibrous tissue, foam cells
  • occasionally, small elongated giant cells

Differential Diagnosis:  

  1. malignant fibrous histiocytoma
  2. eosinophilic granuloma
  3. osteosarcoma
  4. histiocytic lymphoma
  5. pyogenic osteomyelitis


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